How a low-dose combination of Ibuprofen-Paracetamol may be the answer, according to scientific researches
Ibuprofen + Paracetamol: The most effective way to combat body pain
The combination of Ibuprofen and Paracetamol is the most effective over-the-counter (OTC) pain medicine among OTC pain medicines studied according to a 2015 scientific review by the world-renowned independent research institution, Cochrane. Cochrane evaluates health interventions, best known for their systematic reviews, which select only high-grade clinical researches in assessing the effectiveness and safety of medicines.
Among the different formulations studied, which include ibuprofen, naproxen, paracetamol, and aspirin, the combination Ibuprofen+Paracetamol had the highest success rate in providing pain relief. This combination works because while paracetamol and ibuprofen are both painkillers, they also have different mechanisms of action. As a combination, it has both analgesic and anti-inflammatory properties, indicating that it can reduce pain and swelling which also causes pain.
Ibuprofen+Paracetamol can work together to effectively fight body pain. According to Unilab Medical Director Dr. Jonas Policarpio, “On one side, ibuprofen inhibits the release of prostaglandins; while on the other side, paracetamols reset the pain threshold in the brain, harnessing synergies to be able to provide better potency even at low doses while maintaining an excellent margin of safety. Their actions then become complementary, and the effect is synergistic. It’s like a one-two punch.”
A low-dose combination for a safe pain relief
With her field mainly requiring physical and muscle work, body pains are frequent for weightlifting champion and Alaxan ambassador Hidilyn Diaz, so she makes sure to address the pain immediately with Alaxan FR.
The same review of studies has also shown that the combination of Ibuprofen+Paracetamol has less adverse effects than placebo which proves that Ibuprofen+Paracetamol is not likely to cause serious harmful effects on our body when used at the recommended dose.
When assessed whether individually or as a combination, Paracetamol is generally perceived to be harmless, but Ibuprofen and other NSAIDs are perceived differently. On the contrary, Ibuprofen has been found safe when used as directed.
A scientific paper titled “Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review” did a comprehensive analysis of published researches on NSAIDs. It concluded that Ibuprofen is ranked among the safest of the NSAID pain relievers. NSAIDs are not all the same when it comes to safety profile. “Risk for GI adverse events, (cardiovascular) side effects, renal, and hepatotoxic effects are very low with ibuprofen compared with other NSAIDs”. This means that Ibuprofen was found to have a very low risk of harm to the gastrointestinal tract, heart, kidney, and liver when taken at the recommended OTC dose.
Another finding of this research was that the health risks were more associated with high therapeutic doses. 200mg Ibuprofen is low in comparison to these prescription-grade medicines.
Among the OTC medications in the Philippines that utilize the effective combination of Ibuprofen+Paracetamol is ALAXAN. It combined a lower level of Ibuprofen & Paracetamol (200mg Ibuprofen and 325mg Paracetamol) to improve its safety profile while harnessing the synergistic effect of the 2 ingredients. It offers relief of mild to moderately severe pain such as muscle pain, arthritis, rheumatism, sprain, strain, tendonitis, backache, stiff neck, tension headache, dysmenorrhea, toothache, pain after tooth extraction and minor surgical operations.
Trusted by many Filipinos for decades, there has been no serious side effects attributable to Ibuprofen+Paracetamol (ALAXAN). That is because of its low-dose combination of Ibuprofen & Paracetamol. This along with following the right dosage helps Ibuprofen+Paracetamol (ALAXAN) to deliver worry-free pain relief for Filipinos.
Proper Dosage is a Must
Boxing legend and Alaxan ambassador Manny Pacquiao has been a user of Alaxan FR for 22 years, helping him relieve body pains from both athletic and personal activities. Pacquiao affirmed that he hasn’t experienced any side effects from taking the pain medication over the years.
As with any treatment, following the recommended dosage is a must. For adults and children 12 years and older, the proper dose is 1 tablet or capsule every 6 hours. Do not take longer than 10 days, unless directed by a doctor. Consult your doctor too if you have any serious medical condition. Like any medicine, do not take Ibuprofen+Paracetamol if you have allergies.
For more information about Ibuprofen+Paracetamol (ALAXAN), visit their Facebook Page at @AlaxanFastRelief or visit their website: more about Alaxan. If symptoms persist, consult your doctor.
